Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD)
A statistical correlation was found between the advent of the use of refrigeration in the United States and various parts of Europe and the rise of the disease. There is also a tentative association between Candida colonization and Crohn's disease.
Still, these relationships between specific pathogens and Crohn's disease remain unclear. The increased incidence of Crohn's in the industrialized world indicates an environmental component. Crohn's is associated with an increased intake of animal proteinmilk proteinand an increased ratio of omega-6 to omega-3 polyunsaturated fatty acids.
Consumption of fish protein has no association. Although stress is sometimes claimed to exacerbate Crohn's disease, there is no concrete evidence to support such claim. During a colonoscopybiopsies of the colon are often taken to confirm the diagnosis. Certain characteristic features of the pathology seen point toward Crohn's disease; it shows a transmural pattern of inflammationmeaning the inflammation may span the entire depth of the intestinal wall.
There is usually an abrupt transition between unaffected tissue and the ulcer—a characteristic sign known as skip lesions. Under a microscope, biopsies of the affected colon may show mucosal inflammation, characterized by focal infiltration of neutrophilsa type of inflammatory cell, into the epithelium. This typically occurs in the area overlying lymphoid aggregates. These neutrophils, along with mononuclear cellsmay infiltrate the cryptsleading to inflammation crypititis or abscess crypt abscess.
The granulomas of Crohn's disease do not show "caseation", a cheese-like appearance on microscopic examination characteristic of granulomas associated with infections, such as tuberculosis. Biopsies may also show chronic mucosal damage, as evidenced by blunting of the intestinal villiatypical branching of the crypts, and a change in the tissue type metaplasia. One example of such metaplasia, Paneth cell metaplasiainvolves the development of Paneth cells typically found in the small intestine and a key regulator of intestinal microbiota in other parts of the gastrointestinal system.
The diagnosis of Crohn's disease can sometimes be challenging,  and many tests are often required to assist the physician in making the diagnosis. Disease in the small bowel is particularly difficult to diagnose, as a traditional colonoscopy allows access to only the colon and lower portions of the small intestines; introduction of the capsule endoscopy  aids in endoscopic diagnosis.
Giant multinucleate cellsa common finding in the lesions of Crohn's disease, are less common in the lesions of lichen nitidus. CT scan showing Crohn's disease in the fundus of the stomach. Endoscopic biopsy showing granulomatous inflammation of the colon in a case of Crohn's disease. Section of colectomy showing transmural inflammation. Crohn's disease is one type of inflammatory bowel disease IBD.
It typically manifests in the gastrointestinal tract and can be categorized by the specific tract region affected. A disease of both the ileum the last part of the small intestine that connects to the large intestineand the large intestine, Ileocolic Crohn's accounts for fifty percent of cases. Crohn's ileitis, manifest in the ileum only, accounts for thirty percent of cases, while Crohn's colitis, of the large intestine, accounts for the remaining twenty percent of cases and may be particularly difficult to distinguish from ulcerative colitis.
Gastroduodenal Crohn's disease causes inflammation in the stomach and the first part of the small intestine called the duodenum. Jejunoileitis causes spotty patches of inflammation in the top half of the small intestine, called the jejunum. However, individuals affected by the disease rarely fall outside these three classifications, with presentations in other areas. Crohn's disease may also be categorized by the behavior of disease as it progresses.
These categorizations formalized in the Vienna classification of the disease. Stricturing disease causes narrowing of the bowel that may lead to bowel obstruction or changes in the caliber of the feces. Penetrating disease creates abnormal passageways fistulae between the bowel and other structures, such as the skin.
Inflammatory disease or nonstricturing, nonpenetrating disease causes inflammation without causing strictures or fistulae. A colonoscopy is the best test for making the diagnosis of Crohn's disease, as it allows direct visualization of the colon and the terminal ileumidentifying the pattern of disease involvement. On occasion, the colonoscope can travel past the terminal ileum, but it varies from person to person.
During the procedure, the gastroenterologist can also perform a biopsy, taking small samples of tissue for laboratory analysis, which may help confirm a diagnosis. Finding a patchy distribution of disease, with involvement of the colon or ileum, but not the rectumis suggestive of Crohn's disease, as are other endoscopic stigmata.
A small bowel follow-through may suggest the diagnosis of Crohn's disease and is useful when the disease involves only the small intestine. Because colonoscopy and gastroscopy allow direct visualization of only the terminal ileum and beginning of the duodenumthey cannot be used to evaluate the remainder of the small intestine.
As a result, a barium follow-through X-ray, wherein barium sulfate suspension is ingested and fluoroscopic images of the bowel are taken over time, is useful for looking for inflammation and narrowing of the small bowel. They remain useful for identifying anatomical abnormalities when strictures of the colon are too small for a colonoscope to pass through, or in the detection of colonic fistulae in this case contrast should be performed with iodate substances.
CT and MRI scans are useful for evaluating the small bowel with enteroclysis protocols. A complete blood count may reveal anemia, which commonly is caused by blood loss leading to iron deficiency or by vitamin B 12 deficiency, usually caused by ileal disease impairing vitamin B 12 absorption. Rarely autoimmune hemolysis may occur.
Erythrocyte sedimentation rate ESR and C-reactive protein help assess the degree of inflammation, which is important as ferritin can also be raised in inflammation. Anemia of chronic disease results in a normocytic anemia. Other causes of anemia include medication used in treatment of inflammatory bowel disease, like azathioprine, which can lead to cytopenia, and sulfasalazine, which can also result in folate deficiency. Testing for Saccharomyces cerevisiae antibodies ASCA and antineutrophil cytoplasmic antibodies ANCA has been evaluated to identify inflammatory diseases of the intestine  and to differentiate Crohn's disease from ulcerative colitis.
Low serum levels of vitamin D are associated with Crohn's disease. The most common disease that mimics the symptoms of Crohn's disease is ulcerative colitis, as both are inflammatory bowel diseases that can affect the colon with similar symptoms. It is important to differentiate these diseases, since the course of the diseases and treatments may be different. In some cases, however, it may not be possible to tell the difference, in which case the disease is classified as indeterminate colitis.
There is no cure for Crohn's disease and remission may not be possible or prolonged if achieved. In cases where remission is possible, relapse can be prevented and symptoms controlled with medication, lifestyle and dietary changes, changes to eating habits eating smaller amounts more oftenreduction of stress, moderate activity, and exercise.
Surgery is generally contraindicated and has not been shown to prevent remission. Adequately controlled, Crohn's disease may not significantly restrict daily living. Certain lifestyle changes can reduce symptoms, including dietary adjustments, elemental dietproper hydrationand smoking cessation. Diets that include higher levels of fiber and fruit are associated with reduced risk, while diets rich in total fats, polyunsaturated fatty acids, meat, and omega-6 fatty acids may increase the risk of Crohn's.
Eating small meals frequently instead of big meals may also help with a low appetite. A food diary may help with identifying foods that trigger symptoms. Some people should follow a low fiber diet to control acute symptoms especially if fibrous foods cause symptoms. They may have specific dietary intolerances not allergies. Smoking may worsen symptoms, and stopping is recommended.
Acute treatment uses medications to treat any infection normally antibiotics and to reduce inflammation normally aminosalicylate anti-inflammatory drugs and corticosteroids. When symptoms are in remission, treatment enters maintenance, with a goal of avoiding the recurrence of symptoms. Prolonged use of corticosteroids has significant side-effects ; as a result, they are, in general, not used for long-term treatment.
Alternatives include aminosalicylates alone, though only a minority are able to maintain the treatment, and many require immunosuppressive drugs. Medications used to treat the symptoms of Crohn's disease include 5-aminosalicylic acid 5-ASA formulations, prednisoneimmunomodulators such as azathioprine given as the prodrug for 6-mercaptopurinemethotrexate infliximabadalimumab certolizumab vedolizumabustekinumab and natalizumab.
The gradual loss of blood from the gastrointestinal tract, as well as chronic inflammation, often leads to anemia, and professional guidelines suggest routinely monitoring for this. Guidelines vary as to how iron should be administered. Besides, other problems include a limitation in possible daily resorption and an increased growth of intestinal bacteria. Some  advise parenteral iron as first line as it works faster, has fewer gastrointestinal side effects, and is unaffected by inflammation reducing enteral absorption.
Other guidelines  advise oral iron as first-line with parenteral iron reserved for those that fail to adequately respond as oral iron is considerably cheaper.
Blood transfusion should be reserved for those who are cardiovascularly unstable, due to its relatively poor safety profile, lack of long-term efficacy, and cost. Crohn's cannot be cured by surgeryas the disease eventually recurs, though it is used in the case of partial or full blockage of the intestine. After the first surgery, Crohn's usually comes back at the site where the diseased intestine was removed and the healthy ends were rejoined; Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD) can also come back in other locations.
After a resection, scar tissue builds up, which can cause strictureswhich form when the intestines become too small to allow excrement to pass through easily, which can lead to a blockage.
After the first resection, another resection may be necessary within five years. There is no statistical significance between strictureplasty alone versus strictureplasty and resection in cases of duodenal involvement. Postsurgical recurrence of Crohn's disease is relatively common.
Crohn's lesions are nearly always found at the site of the resected bowel. The join or anastomosis after surgery may be inspected, usually during a colonoscopy, and disease activity graded. The "Rutgeert's score" is an endoscopic scoring system for postoperative disease recurrence in Crohn's disease.
Mild postsurgical recurrences of Crohn's disease are graded i1 and i2, moderate to severe recurrences are graded i3 and i4. Based on the score, treatment plans can be designed to give the patient the best chance of managing the recurrence of the disease.
Short bowel syndrome SBS, also short gut syndrome or simply short gut is caused by the surgical removal of part of the small intestine. It usually develops in those patients who have had half or more of their small intestines removed. Short bowel syndrome is treated with changes in diet, intravenous feeding, vitamin and mineral supplements, and treatment with medications. In some cases of SBS, intestinal transplant surgery may be considered; though the number of transplant centres offering this procedure is quite small and it comes with a high risk due to the chance of infection and rejection of the transplanted intestine.
Bile acid diarrhea is another complication following surgery for Crohn's disease in which the terminal ileum has been removed. This leads to the development of excessive watery diarrhea.
It is usually thought to be due to an inability of the ileum to reabsorb bile acids after resection of the terminal ileum and was the first type of bile acid malabsorption recognized. Crohn's may result in anxiety or mood disordersespecially in young people who may have stunted growth or embarrassment from fecal incontinence.
As of [update] there is a small amount of research looking at mindfulness-based therapieshypnotherapy, and cognitive behavioural therapy. It is common for people with Crohn's disease to try complementary or alternative therapy. Crohn's disease is a chronic condition for which there is no known cure. It is characterised by periods of improvement followed by episodes when symptoms flare up. With treatment, most people achieve a healthy weight, and the mortality rate for the disease is relatively low.
It can vary from being benign to very severe, and people with CD could experience just one episode or have continuous symptoms. It usually reoccurs, although some people can remain disease-free for years or decades.
The percentage of people with Crohn's disease has been determined in Norway and the United States and is similar at 6 to 7. Crohn's disease begins most commonly in people in their teens and 20s, and people in their 50s through to their 70s. It usually affects female children more severely than males.
The incidence of Crohn's disease is increasing in Europe  and in newly industrialised countries. Inflammatory bowel diseases were described by Giovanni Battista Morgagni — and by Scottish physician T Kennedy Dalziel in Later that year, he, along with colleagues Leon Ginzburg and Gordon Oppenheimer, published the case series "Regional ileitis: a pathologic and clinical entity".
However, due to the precedence of Crohn's name in the alphabet, it later became known in the worldwide literature as Crohn's disease. Some evidence supports the hypothesis that the bacterium Mycobacterium avium subspecies paratuberculosis MAP is a cause of Crohn's disease see also Johne's disease.
As a result, researchers are looking at the eradication of MAP as a therapeutic option. Crohn's is common in parts of the world where helminthic colonisation is rare and uncommon in those areas where most people carry worms.
Infections with helminths may alter the autoimmune response that causes the disease. Trials of extracts from the worm Trichuris suis showed promising results when used in people with IBD. There is no good evidence that thalidomide or lenalidomide is useful to bring about or maintain remission.
From Wikipedia, the free encyclopedia. It is not to be confused with Croan or Crone. Medical condition. Main article: Management of Crohn's disease. Main article: List of people diagnosed with Crohn's disease.
PMID Archived from the original on December 8, Retrieved December 8, Clinical Gastroenterology. World Gastroenterology Organization. August Archived from the original PDF on March 14, Retrieved March 13, The American Journal of Gastroenterology.
S2CID PMC Journal of Clinical Gastroenterology. Current Drug Targets. The Journal of Experimental Medicine. Expert Review of Clinical Immunology. World Journal of Gastroenterology.
Archived from the original on June 6, World J Gastroenterol. Nature Genetics. Retrieved February 10, Journal of Gastroenterology and Hepatology.
Current Opinion in Gastroenterology. The Lancet. Archived from the original on October 20, Retrieved Oct Translate. Diagnosis and Control of Johne's Disease. ISBN International Journal of Colorectal Disease. Archived from the original on November 21, Retrieved December 11, The British Journal of Surgery.
ISSN Gastrointestinal Endoscopy. J Clin Med. Archives of Disease in Childhood. The Netherlands Journal of Medicine Submitted manuscript. Scandinavian Journal of Gastroenterology. March Robbins and Cotran: Pathologic Basis of Disease 7th ed. Philadelphia, Pennsylvania: Elsevier Saunders.
The PAE did not work for me but caused no problems either. My enlarged median lobe may have had to do with the outcome. Thanks Thomas, Sorry it didn't work for you. Seems to be a bit hit and miss. Unfortunately, will have to go to U.
As you had it almost 5 years ago, I will see what the radiologist tells me in a few days. The success rate have increased for PAE since then. Thanks a lot. Henry, when Dr. Clinical success rate is something different and I would say that is lower.
I just don't see this high of clinical success following anecdotal reports. I woke up half way through the procedure absolutely busting for a pee so they had to stop everything and insert a catheter to drain me. When you are strapped to the table with a catheter in your artery you can't get up and go to the toilet. If you are suffering from 'urgency' pre PAE I would recommend you ask for a catheter for the duration of the procedure.
My understanding is that health care costs in the USA are aproximately tripple to quadruple what you will pay in Australia. I would look at providers in Asia if you are looking for affordability. Too bad the centre in Macquarie is only doing FLA for prostate cancer. Unless someone tells me differently, no other place in Australia is doing FLA.
The cash cost should be significantly less. The lobe protruded into my prostate with a flap causing a valve effect. The median lobe did shrink but I still have the flap which gives me far less problems now than it used to give me. It affects me worst at night when I wake with a full bladder after a deep period of sleep.
It can take me three voids about 10 minutes apart to empty my bladder but at least I can empty it and no longer suffer from acute bladder infections. I still experience 'urgency' but this is mainly caused by running water. When I turn on a water tap to wash my hands or to get a glass of water something inside me decides I urgently need to pee.
Quite strange! I am on the cusp of deciding to have a urologist take another look at my entire system so I can better understand what I am dealing with. I used Henrys apple cider vinegar and cranberry brew with some success. I have also tried pure gum turpentine and sugar and had some success too. I believe that they both work to get rid of the low level UT infections which affect the ability of my median lobe flap to block my bladder exit.
I think that the flap may enlarge when it becomes inflamed. It is the improvement that the brews mentioned above have given me that is delaying my visit to a urologist. I have just now stumbled across a very exciting enlarged prostate treatment option in China.
I was looking at Ron Bazars Canada Natural Prostate Health web site and he is championing a clinic in China that he has used to successfully treat his own gm prostate by a method targeting the pathogens that live in the prostate tissue and cause the enlargement. I won't name the clinic as I am not sure that moderators will like that so I advise you go to Ron Bazars site and find the link to China yourself.
I have been taking Pure Gum Turpentine and sugar for exactly the same purpose, to rid my prostate of pathogens. Low Odour Kerosene and sugar will do the same thing. They are 'old mountain remedies'. Look these up too and make up your own mind. They are both available off the shelf at Bunnings Hardware for 10 bucks. I am afraid I will stay away from Asian remedies.
I just wouldn't trust my health with these people even if it may be cheaper. The enlarged median lobe, does act as a flap particularly as the intra-bladder pressure increases which makes voiding the bladder more difficult. It also irritates the opening to the urethra which makes you want to go more often. Ultimately, once you make a decision, you have to trust the expertise of the practitioner.
I don't mind spending the money, but you want some degree of certainty that it will work to a reasonable degree. Edited 7 months ago. Turpentine and fertilizer????????? Is thing with doctor's blessing? Hard to believe this is safe. We are starting to hear how dangerous natural herbs and other substances can be to our bodies.
I think the Apple vinegar cocktail is as far as I am willing to go. My opinion. There have been several people on this web site who described an enlarged median lobe acting like a ball valve with the bladder neck. In particular there was one person, stan, who posted an MRI picture of his enlarged median lobe, and it was quite large. Here is the quote from University of Washington in Seattle from Feb Its crazy.
See link. It's obvious that our healthcare system is completely out of whack. It's become predatory. It's the No. I went to an urologist in South America who had been training with Dr Pisco in Pertugal when i asked how many procedures he said Immediately left and went to VIV.
I believe the U. By the way I saw a general surgeon today because of a hernia problem. I am booked in Thursday to have the procedure. One night in hospital will be fully covered. Those charges are probably low compared to U. The worry about going to the U. When I travel I always vuy travel insurance. However, if you look at this blog there is a wealth of information on it. That is how I choose Dr.
Bagla at VIV based on experience. My own procedure turns into a great example of the right choice as does others that preceded me with VIV. Money and experience drives your decision and that is understandable.
My only concern in the U. Here she knows the medical system and has influence; there she would just be a visitor. My wife has been practicing for 48 years so she knows the goid and bad in her profession.
Has anyone out there had a "Prostate Artery Embolization?? New discussion Reply. Haven't had it, but would love to hear your experiences. From the little I read, sounds very promising without some of the sexual side effects from Turp and laser. ChuckP jimjames. Iam still getting up anywhere from 4 to 5 times a night the same as before the procedure.
The flow is a little stronger but nothing to write home about. So basically Iam still frustrated and trying to stay positive. The Interventional Radiologist told me it would take anywhere from 30 days to 6 months to see positive results.
I guess we'll see. Please feel free to ask any questions but as of today I would NOT recommend it. Sorry results aren't coming in yet. Has your radiologist done an imaging study since your PAE to see if your prostate has gotten any smaller?
Other than the frequency you mention, what other symptons did you have prior to the PAE? What about retention, for example. Was that every a problem or was it more frequency.
I am considering having the procedure and would appreciate your feedback. I had no side effects whatsoever. Thanks so much for your reply. It is very helpful. Godsloveforus1 ChuckP. Sharebare caringbah. I'm up up to 6 times per night. Is everything still ok with you? Hi Caringbah, I've been "managing" the urinary issues for over 10 years now, turned for much worse recently with the uro advising TURP as the only option.
I am in Aus Melbourne. I am on flowmaxtra with some imporvment which buys me some time. Was your surgery covered by Medicare?
Hi Rama, He's either ignorant or deceptive Hi Sharebare, i just noticed your comment now. ChrisRed caringbah. Hi there its Chris I contacted you some time ago on here regarding a horrible experience with anaphalctic shock whilst having a CT scan and MRI with Doctor Schlappoff was wondering how your PAE is going any side effects or problems?
I contacted Dr Schlapoff again asking if there is anything I can do due with regard my allergy to the contrasts so I can have the PAE done he called me and said he can do it under controlled conditions but I never heard back from him??
Im aware that you are also allergic to the contrasts too and wondered what he did with you regarding this? So I may be able to discuss the same measures with him and also wanted to know how you are going and if all went well with your PAE and any further problems or progressions? Hi Chris, PAE is great I'm very happy. Hello Chris, I wanted to ask what kind of reaction you had to the dye?
The good news is the PAE seems to be slowly working. Hi I am interested in getting this PAE procedure done How can Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD) get a contact no. Hi Peter, you can call the radiology department at Livetpool Hospital and tell them that you would like to make an appointment with Dr Schlapoff for PAE or else you can private message me and I can give you a number.
I'm planning on having it done in 3 weeks. Was your radiologist Bagla? Hi Joe My name is Fouad. Hello Fouad, sorry I cant help you much. I am 7 months out from mine, and have actually gotten much worse. You might check with some of the other guys. I had what appears to be a bad reaction to the beads they used, and my prostate stays in a constant state of inflamation. Which makes it very difficult to pee. I also have sores on my arms,legs and crotch that will not go away.
The Doc has told me there is no way to relieve all the symptoms other than a complete prostate removal, since there is no way to remove the beads. Have you not gotten any results yet? I still having the inflammation after 3 week of having the procedure. Where did you have it done? Also did you take the prednisone they gave you? Hopefully you will still improve. I had mine at UNC also. Hang in there, you are still in that time frame Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD) hopefully you will still improve.
You might contact Dr. Isaacson again, and ask his advice. He is very responsive and helpful. You can reach him through his office by phone. Hi Joe, Thanks for your post. Wow Bob it sounds like you have tried it all.
I would never discourage anybody from trying the pae especially with a prostate as large as yours. Mine was only 45 gms lol. Not sure where I will wind up but its probably not a good outcome. I keep hoping things will improve but not so far. Hi Joe, Thanks for your posts.
Wow Bob no offense but I thought I was the only guy that had luck like thst lol. You have really been thru the wringer buddy. I would contact Dr. Bagla of Vascular Institue of Virginia and get another opinion. I have had fantastic results with absolutely no negative side effects. Thanks Terry, If I have no other options I'll do that. I'm 71 yrs. Hi Gary, Curious as to why your procedure took so long. Hi Gary, Thanks for your post.
PAEs have had significantly greater success for large prostates without median lobe issues. I guess the question is whther the median lobe is affected at all by the procedure. It is part of the prostate, does it get a similar shrinkage, or is it unaffected. Good luck! I guess we can both afford to wait as neither one of us is now in retention or has a large PVR.
It would be great if they figure out how to shrink the median lobe as well. Hi Gary, Thanks for the info. Hi, could you give me details for Dr Schlapoff? Hi Allan, Call Liverpool hospital in Sydney and ask for the radiology department. When you meet him say hello for me. Cheers Peter from Caringbah. Les peter More men need to know about this.
I'm very pleased my GP found Dr Ranatunga and referred me. So it is available in Melbourne. Hi Caringbah, just pm'd you. Ozrural caringbah. Had they used a catheter on you during the pae? That may have accounted for some of the burning. Thanks for the wonderful update.
Glad it went well for you Oz. I think about ruination all day. Dear Caringbah my name is Roberto G. Hi Roberto, Just checked my less than complete notes that I take when reading posts and came across three posters from AUS that might be helpful for you to search for: Les and Wanderinghans were definitely in this discussion. Joe you said you had this done at UNC. Where is this? Were you in a clinical trial? Hi Jim, Have you heard what the side effects from Gl surgery are,besides sexual side effects?
Hi Jim, I am concerned not to touch the speedi cath ,so i bought some sterile pre powdered gloves. Is this powerdered glove good to use for this? Jimbless you for all the good you have done to help all of us on thei form. Hi Frank, I have used the speedicaths. Hi Fouad. I am thinking of getting the procedure at UNC. Can you give me a breakdown of how you did in the weeks and months following the procedure.
Did you have any problems with urination in the weeks after and was there any pain. Have you had improvement in urination and getting up at night to pee?
Any sexually issues like retrograde ejaculating? Dido Dr. Isaacson perform our rocedure? Hi terry, I am considering using Dr bagla and I would like to know how long ago Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD) you have your paw done? How long did it take? How long is recovery? And can you add any information that I may be interested in. Hello Peter are you still seeing improvements?
I am about to have the PAE done just a little concerned. Can you tell me how do they know How many pallets to use? Can they Kill the prostate if they use to much? Hi, my name is Gunter I am from Germany.
I will PM you the info. Hi caringbah, I am 62 years old, with recently diagnosed BPH. My urologist in Perth does not recommend any treatment. However, I am planning to seek consultation with a radiologist, probably your Dr Schlapoff, to see if I am a suitable candidate for PAE. As it is such a new procedure, I am a little concerned about its long-term efficacy ie two or three years out.
As far as I can see, the operation does not shrink the BPH so much as soften the tissue, allowing urine etc to flow more easily. I would be interested to hear how you ar getting along, a few years after your own operation?
Hi Cosmopug, What are your symptons? Joe, sorry to read about your reaction to the beads. Have things gotten any with your results or reaction in the past 11 months?
Hi Gary, glad you had such good results from the PAE. It has been 11 months since this post. How are things now? I have read a few cases of good results in the short term but return to pre procedure situation after a short time. Hey Richard, thanks for the email. Not lots of improvement, still have the skin spots, I am guessing they are permanent. But I had about 6 good months with no infection, but currently back on the prednisone and antibiotics.
Wouldnt be too bad if I had at least gotten some improvement in the urinary symptoms, but I can not tell any difference at all pre PAE. Really looking at FLA now, to see if thst might be the answer. Thanks for that Jim. I have found a urology clinic that performs FLA for prostate cancer down south of Sydney. I have also emailed my interventional radiologist requesting a follow up consultation and scans to get a better understanding of what is really occurring.
You might also want to check out Dr. He is the lead researcher on Aquablation. Camster jimmyjohn. I had PAE April I was showing some improvement finally early this year. In April, I had the same thing happen. It turned around in about a week. I thought it could be a mild infection. Tried a course of antibiotics. Nothing changed. Thanks Cam I went to Pittsburg once back in Keep me posted on the IRE. Have never heard of it.
Was studying AquaBlation. It still has retrograde ejaculation potential. It has not been approved in the US. When the procedure is done through the urethra, more problems can be expected. Also looking at High Intensity Focused Ultrasound. It has been approved by the FDA for prostate cancer. It is done through the rectum by a transducer. It does not penetrate the rectum.
It is done by a urologist. I talked to the company for about 20 minutes. It would be cashpay for BPH problems.
Can ablate about 10 grams of tissue per hour. It is done under general anesthesia because one cannot move. Outpatient with Foley catheter few days depending. Camster: Aquablation still has retrograde ejaculation potential. Camster jimjames. Hi Camster, There were only three trials that I know about for Aquablation, and so far zero retro in 33 men. Jim, is one of the studies you know about in Albany, NY?
One of the docs involved is Dr. Hi Rich, No. Very late to this forum I had this done and had no good results at all. Prostate did not shrink any at all. Total waste of time and my guy was Bagla. Camster ditzpro. Just a follow-up. This urologist today told me that TUMT microwave has gone by the wayside. He no longer does TUNA. He said it is being replaced by Rezum. I asked him if he does it. He stumbled around for an answer for some reason.
Why - Toxic Waste (3) / Bleeding Rectum - We Will Be Free (CD) know there is an investment in the technology. Last note before bedtime. Something about the myelin around nerves being destroyed in the prostate.
I have never come across that in my research. Camster: My sense is that Aquablation will have retro issues. Jim, I have read that PAE has had some failures, allergic reaction to beads and sometimes just not working at all. But, from what has been posted the results with FLA have been all fantastic. The recovery has been slow for some patients with the catheter, but after 5 weeks every review reports great results with no side effects.
Have you heard of some FLA failures that have not been reported? Hi Cam, I have just finished my antibiotics. Hi Garry, Considering Dr. Jezzaman bob HI Bob I am interested to know if you have any side effects from the Dutasteride? TKM jimmyjohn. TKM Jezzaman. Jezzaman, Have you had a cystoscopy or a urodynamics test? Jim, please do your homework before having this procedure. The amount of radiation you are exposed to is astronomical. Hi Gary, Can you please explain how much radiation.
Here is the question to and the reply that I rec'd from Dr Bagla's office in Jan concerning radiation exposure with PAE at his office: I know from a previous email that you said that the radiation involved for the procedure is less exposure than a typical CT-scan study.
Here is what my research shows. Please print this out and share with Dr. Bagla: I found out that the peak skin exposure to radiation is Rich, I concur with your comments. Hi Gary, As I mentioned, the science part of this is a bit over my head.
Rich, a CAT scan is a diagnostic test. You are exposed to much less radiation. While you are having the PAE for about an hour you are sitting under a florascope. Also when they feed the line or tube or whatever it is to get to your prostate you are also under a device that allows the doctor to follow it through your veins. I question the results of the study. Camster gary It can also be caused by tuberculosis, colon cancer, and enteritis.
If there is blood visible in the stools, it is also known as dysentery. The blood is a trace of an invasion of bowel tissue. Dysentery is a symptom of, among others, ShigellaEntamoeba histolyticaand Salmonella.
Diarrheal disease may have a negative impact on both physical fitness and mental development. Diarrhea can cause electrolyte imbalanceskidney impairmentdehydrationand defective immune system responses. When oral drugs are administered, the efficiency of the drug is to produce a therapeutic effect and the lack of this effect may be due to the medication travelling too quickly through the digestive system, limiting the time that it can be absorbed.
Clinicians try to treat the diarrheas by reducing the dosage of medication, changing the dosing schedule, discontinuation of the drug, and rehydration. The interventions to control the diarrhea are not often effective.
Diarrhea can have a profound effect on the quality of life because fecal incontinence is one of the leading factors for placing older adults in long term care facilities nursing homes. In the latter stages of human digestion, ingested materials are inundated with water and digestive fluids such as gastric acidbileand digestive enzymes in order to break them down into their nutrient components, which are then absorbed into the bloodstream via the intestinal tract in the small intestine.
Prior to defecation, the large intestine reabsorbs the water and other digestive solvents in the waste product in order to maintain proper hydration and overall equilibrium. Chronic diarrhea can be the part of the presentations of a number of chronic medical conditions affecting the intestine. Common causes include ulcerative colitisCrohn diseasemicroscopic colitisceliac diseaseirritable bowel syndromeand bile acid malabsorption. There are many causes of infectious diarrhea, which include virusesbacteria and parasites.
Campylobacter spp. In the elderly, particularly those who have been treated with antibiotics for unrelated infections, a toxin produced by Clostridioides difficile often causes severe diarrhea. Parasites, particularly protozoa e. The broad-spectrum antiparasitic agent nitazoxanide has shown efficacy against many diarrhea-causing parasites. Other infectious agents, such as parasites or bacterial toxins, may exacerbate symptoms.
However, for ill or malnourished individuals, diarrhea can lead to severe dehydration and can become life-threatening. Open defecation is a leading cause of infectious diarrhea leading to death. Poverty is a good indicator of the rate of infectious diarrhea in a population. This association does not stem from poverty itself, but rather from the conditions under which impoverished people live.
The absence of certain resources compromises the ability of the poor to defend themselves against infectious diarrhea. Poverty also restricts the ability to provide age-appropriate, nutritionally balanced diets or to modify diets when diarrhea develops so as to mitigate and repair nutrient losses.
The impact is exacerbated by the lack of adequate, available, and affordable medical care. One of the most common causes of infectious diarrhea is a lack of clean water.
Often, improper fecal disposal leads to contamination of groundwater. This can lead to widespread infection among a population, especially in the absence of water filtration or purification. Human feces contains a variety of potentially harmful human pathogens. Proper nutrition is important for health and functioning, including the prevention of infectious diarrhea. It is especially important to young children who do not have a fully developed immune system.
Zinc deficiencya condition often found in children in developing countries can, even in mild cases, have a significant impact on the development and proper functioning of the human immune system. Children who have lowered levels of zinc have a greater number of instances of diarrhea, severe diarrhea, and diarrhea associated with fever. However, there is some discrepancy when it comes to the impact of vitamin A deficiency on the rate of disease. While some argue that a relationship does not exist between the rate of disease and vitamin A status,  Others suggest an increase in the rate associated with deficiency.
Malabsorption is the inability to absorb food fully, mostly from disorders in the small bowel, but also due to maldigestion from diseases of the pancreas. Causes include: [ citation needed ].
Another possible cause of diarrhea is irritable bowel syndrome IBSwhich usually presents with abdominal discomfort relieved by defecation and unusual stool diarrhea or constipation for at least three days a week over the previous three months. Some medications, such as the penicillum can cause diarrhea. The classes of medications that are known to cause diarrhea are laxatives, antacids, heartburn medications, antibiotics, anti-neoplastic drugs, anti-inflammatories as well as many dietary supplements.
According to two researchers, Nesse and Williamsdiarrhea may function as an evolved expulsion defense mechanism. As a result, if it is stopped, there might be a delay in recovery. The researchers indeed themselves observed that: "Lomotil may be contraindicated in shigellosis. Diarrhea may represent a defense mechanism". A severity score is used to aid diagnosis in children. When diarrhea lasts for more than four weeks a number of further tests may be recommended including: .
A guideline recommended that testing for ova and parasites was only needed in people who are at high risk though they recommend routine testing for giardia. Numerous studies have shown that improvements in drinking water and sanitation WASH lead to decreased risks of diarrhoea. In institutions, communities, and households, interventions that promote hand washing with soap lead to significant reductions in the incidence of diarrhea.
There is limited evidence that safe disposal of child or adult feces can prevent diarrheal disease. Basic sanitation techniques can have a profound effect on the transmission of diarrheal disease.
This lack of access is one of many challenges to proper hygiene in less developed countries. Given that water contamination is a major means of transmitting diarrheal disease, efforts to provide clean water supply and improved sanitation have the potential to dramatically cut the rate of disease incidence. Chlorine treatment of water, for example, has been shown to reduce both the risk of diarrheal disease, and of contamination of stored water with diarrheal pathogens.
Immunization against the pathogens that cause diarrheal disease is a viable prevention strategy, however it does require targeting certain pathogens for vaccination. Similarly, a Cholera vaccine showed a strong reduction in morbidity and mortality, though the overall impact of vaccination was minimal as Cholera is not one of the major causative pathogens of diarrheal disease. Rotavirus vaccine decrease the rates of diarrhea in a population. Dietary deficiencies in developing countries can be combated by promoting better eating practices.
Zinc supplementation proved successful showing a significant decrease in the incidence of diarrheal disease compared to a control group. Breastfeeding practices have been shown to have a dramatic effect on the incidence of diarrheal disease in poor populations. Studies across a number of developing nations have shown that those who receive exclusive breastfeeding during their first 6 months of life are better protected against infection with diarrheal diseases.
Probiotics decrease the risk of diarrhea in those taking antibiotics. In many cases of diarrhea, replacing lost fluid and salts is the only treatment needed. This is usually by mouth — oral rehydration therapy — or, in severe cases, intravenously. Medications such as loperamide Imodium and bismuth subsalicylate may be beneficial; however they may be contraindicated in certain situations. Oral rehydration solution ORS a slightly sweetened and salty water can be used to prevent dehydration.
Standard home solutions such as salted rice water, salted yogurt drinks, vegetable and chicken soups with salt can be given. Home solutions such as water in which cereal has been cooked, unsalted soup, green coconut water, weak tea unsweetenedand unsweetened fresh fruit juices can have from half a teaspoon to full teaspoon of salt from one-and-a-half to three grams added per liter.
Clean plain water can also be one of several fluids given. A WHO publication for physicians recommends a homemade ORS consisting of one liter water with one teaspoon salt 3 grams and two tablespoons sugar 18 grams added  approximately the "taste of tears" .
Rehydration Project recommends adding the same amount of sugar but only one-half a teaspoon of salt, stating that this more dilute approach is less risky with very little loss of effectiveness.
Appropriate amounts of supplemental zinc and potassium should be added if available. But the availability of these should not delay rehydration. As WHO points out, the most important thing is to begin preventing dehydration as early as possible. Vomiting often occurs during the first hour or two of treatment with ORS, especially if a child drinks the solution too quickly, but this seldom prevents successful rehydration since most of the fluid is still absorbed.
WHO recommends that if a child vomits, to wait five or ten minutes and then start to give the solution again more slowly. Drinks especially high in simple sugars, such as soft drinks and fruit juices, are not recommended in children under five as they may increase dehydration. A too rich solution in the gut draws water from the rest of the body, just as if the person were to drink sea water. The WHO recommends a child with diarrhea continue to be fed. Continued feeding speeds the recovery of normal intestinal function.
In contrast, children whose food is restricted have diarrhea of longer duration and recover intestinal function more slowly. The WHO states "Food should never be withheld and the child's usual foods should not be diluted. Breastfeeding should always be continued. Antidiarrheal agents can be classified into four different groups: antimotility, antisecretory, adsorbent, and anti-infectious.
While bismuth compounds Pepto-Bismol decreased the number of bowel movements in those with travelers' diarrhea, they do not decrease the length of illness. Diosmectitea natural aluminomagnesium silicate clay, is effective in alleviating symptoms of acute diarrhea in children,  and also has some effects in chronic functional diarrhea, radiation-induced diarrhea, and chemotherapy-induced diarrhea.
Racecadotril an antisecretory medication may be used to treat diarrhea in children and adults. Bile acid sequestrants such as cholestyramine can be effective in chronic diarrhea due to bile acid malabsorption. Therapeutic trials of these drugs are indicated in chronic diarrhea if bile acid malabsorption cannot be diagnosed with a specific test, such as SeHCAT retention.
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